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. 2023 Jan 6;12:1105454. doi: 10.3389/fonc.2022.1105454

Figure 4.

Figure 4

The model can preserve the structural characteristics of the original tumor, has advantages in simulating the drug concentration layer related to the treatment and can obtain IC50 that is closer to the real data of the human body. It can preserve the intra-tumor and inter-patient heterogeneity, drug response, and drug resistance characteristics, and help realize personalized targeted drug susceptibility testing.