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. 2023 Jan 6;9:1025249. doi: 10.3389/fvets.2022.1025249

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Copyright © 2023 Salinas, Barriga, Albornoz, Alarcon, Quiroga, Uberti, Sarmiento, Henriquez, Ehrenfeld, Burgos and Moran.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tamoxifen triggers netosis mainly of the sprNETS type. Representative fluorescence of equine PMNs treated with TX (10 μM) and marked with DNA staining PicoGreen^TM. Strand-like NETs structures marked with PicoGreen^TM (green) and citrullinated histone H4 antibody (red). Note the formation of sprNETs (consist of smooth, elongated, cobweb-like structures of decondensed chromatin, composed exclusively of fine fibers). Scale bars = 30μm.