FIG. 1.

Time course of fluid accumulation into the ileal lumen during serovar Typhimurium infection from 5 min through 12 h postinfection. Each data point represents the average (± standard deviation) of four independent experiments. ∗, Values corresponding to wild-type infected loops (IR715) are significantly higher than those for the uninfected controls and loops infected with sopB mutant from 3 to 12 h postinfection (P < 0.05). ∗∗, Values corresponding to sopB-infected loops are significantly higher than those for uninfected controls and significantly lower than wild-type infected loops (IR715) from 8 to 12 h postinfection (P < 0.05).