Table 5. Half Inhibitory (IC50) Values of 2, 3, or 4 in MDA-MB-231 or HCC38 Breast Cancer, HCT116 Colorectal Carcinoma, T24 Bladder Cancer Cell Lines, or the MCF10A Non-Tumorigenic Epithelial Cell Line (72 h Treatment)a.
| complex | MDA-MB-231 | HCC38 | HCT116 | T24 | MCF10A |
|---|---|---|---|---|---|
| cisplatin | 32.5 ± 11.7 | 4.5 ± 0.3 | 5.0 ± 1.4 | 1.5 ± 0.5 | 26.5 ± 8.2 |
| 2 | >100 | >100 | 53.7 ± 9.9 | 34.4 ± 3.3 | >100 |
| 3 | 21.8 ± 2.9 | 3.8 ± 2.5 | 16.4 ± 1.4 | 28.0 ± 4.4 | >100 |
| 4 | 20.5 ± 9.6 | 16.5 ± 4.2 | 9.9 ± 1.8 | 29.9 ± 2.3 | 63.1 ± 21.0 |
Cisplatin treatment is included for comparison. Data are mean ± SD of three independent experiments.