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. 2023 Jan 6;145(2):1236–1246. doi: 10.1021/jacs.2c11111

Table 5. Half Inhibitory (IC50) Values of 2, 3, or 4 in MDA-MB-231 or HCC38 Breast Cancer, HCT116 Colorectal Carcinoma, T24 Bladder Cancer Cell Lines, or the MCF10A Non-Tumorigenic Epithelial Cell Line (72 h Treatment)a.

complex MDA-MB-231 HCC38 HCT116 T24 MCF10A
cisplatin 32.5 ± 11.7 4.5 ± 0.3 5.0 ± 1.4 1.5 ± 0.5 26.5 ± 8.2
2 >100 >100 53.7 ± 9.9 34.4 ± 3.3 >100
3 21.8 ± 2.9 3.8 ± 2.5 16.4 ± 1.4 28.0 ± 4.4 >100
4 20.5 ± 9.6 16.5 ± 4.2 9.9 ± 1.8 29.9 ± 2.3 63.1 ± 21.0
a

Cisplatin treatment is included for comparison. Data are mean ± SD of three independent experiments.