Table 1.
List of CTCs biomarkers and its clinical use in CRC.
| Biomarkers | Methods | Clinical use |
|---|---|---|
| EpCAM | CellSearchTM, CanPatrolTM | Predictive and prognostic |
| CEA | RT-PCR | Prognostic |
| CK19 | RT-PCR, CK19-Epispot | Prognostic |
| CD133 | Drug sensitivity analysis of CTC lines | Prognostic |
| CKs | RT-PCR | Prognostic |
| VIM | CanPatrolTM | Prognostic |
| TWIST1 | CanPatrolTM | Prognostic |
| CD26 | Drug sensitivity analysis of CTC lines | Prognostic |
| CD44v6 | Drug sensitivity analysis of CTC lines | Prognostic |
| KRAS | Label-free Vortex technology | Prognostic |
| BRIEF | Label-free Vortex technology | Prognostic |
| PI3KCA | Label-free Vortex technology | Prognostic |
| AKT2 | CanPatrolTM | Prognostic |
| SNAI1 | CanPatrolTM | Prognostic |