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. 2022 Dec 29;10(1):ofac706. doi: 10.1093/ofid/ofac706

Table 2.

Summary of Randomized Controlled Trials of Oral vs IV-Only Therapy

Diagnosis No. of RCTs Demonstrating IV > Oral No. of RCTs Demonstrating Oral ≥ IV References
Osteomyelitis 0 9 (all equal) [103–111]
Bacteremia 0 10 (8 equal, 2 superior cure for oral) [109, 112–120]
Endocarditis 0 3 (2 equal, 1 superior mortality for oral) [121–123]

Abbreviations: IV, intravenous; RCT, randomized controlled trial.