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. 2022 Nov 28;38(1):28–68. doi: 10.1093/her/cyac035

Table II.

Results (for studies investigating association of diet quality with mental health parameters)

Hypothesis outcome Effect sizea
Author, year Diet quality tool Depression tool Dietary assessment Model Adjustment Result OR, HR or RR, β coefficients, or other statistics 1 2 3 Small Medium Large
Mental health parameter: depression
Açik and Cakiroglu, 2019 [44] DII ZSRDS 3-day food records Multivariate logistic regression analysis Age, smoking, alcohol, PA level, anthropometric measurements Poor diet quality was positively associated with depression scores OR = 2.90
(95% CI 1.51–5.98)
X X
Jeffers et al., 2019 [45] General estimating equations of dietary quality PANAS EMA Generalized estimating equations Each food item was examined as a predictor in separate models and each of the negative and positive effect was used as separate dependent variables There was a positive association between fruits and positive affect (i). There was a positive association between sugary foods and negative affect (ii) (i) Estimate = 1.37 (SE 0.49, P < 0.005) (ii) Estimate = 0.06
(SE 0.03, P < 0.02)
X X
Faghih et al., 2020 [46] DASH DASS-21 Semi-quantitative FFQ Pearson’s correlation coefficients Socio-economic, lifestyle and anthropometric characteristics There was a negative correlation between diet quality and depression Pearson’s coefficient = −0.434 (P < 0.001) X X
Ramón-
Arbués et al., 2019 [64]
HEI DASS-21 N/A Pearson’s correlation coefficients Age, sex, study area, habitual residence, relationship status, height, weight, perceived economic situation, smoking, alcohol consumption, PA and sedentary lifestyle There was no significant association between HEI and depression N/A X
Attlee et al., 2022 [65] E-DII DASS-21 24-h dietary recall Logistic regression analysis Body habitus measures (BMI and WC), nutrient intakes and specific food groups, smoking status, PA categories No significant association N/A X
Lee et al., 2022 [63] N/A DASS-21 FFQ Linear regression Age, gender, ethnicity, relationship status, employment, income, living arrangements, number of children, education The likelihood of more severe depression increased with higher consumption of grain (cereal) food (i) and lower consumption of dairy products (ii) (i) β = 1.61, 95% CI, 0.22, 3.01
(ii) β = −3.38, 95% CI, −5.39, −1.38
X X
Stanton et al., 2021 [62] N/A DASS-21 Previously validated Australian FFQ Multivariate regression analysis Gender, age, enrolment, ethnicity, relationship status, living arrangement, work, health conditions Intake of snack foods was associated with higher depression scores β = 8.66, P < 0.05 X X
Abramson 2017 [119] HEI BDI FFQ
(5 days)
Spearman and partial correlations Age, gender There was no significant association between HEI and depression N/A X
Quehl et al., 2017 [48] HEI CES-D 3-day food records Linear regression Age Diet quality was negatively associated with depression scores β= −0.016
(95% CI −0.029 to −0.003, P = 0.017)
X X
Sakai et al. 2017 [47] DQS CES-D Diet history questionnaire Multivariate analysis BMI, current smoking,
medication use, self-reported level of stress, dietary reporting status, PA, energy intake and living alone
Diet quality was negatively associated with depression OR for depression in highest versus lowest quintiles of diet quality was 0.65
(95 % CI 0.50–0.84, P = 0.0005)
X X
Hamazaki et al., 2015 [50] N/A CES-D Customary intake frequency Multivariate logistic analysis Age, gender, academic performance, friendships, financial matters, smoking status, consumption of alcohol, PA Fish intake was negatively associated with depression OR= 0.65, (95% CI 0.46–0.92) of highest versus lowest category of fish consumption X X
Liu et al., 2007 [51] N/A CES-D FFQ Stepwise logistic regression Gender, grade, city, perceived weight, smoking level and alcohol use Risk of depression was increased with
low fruit frequency and decreased with low ready to eat food, low snack food frequency and low fast food frequency.
OR for depression was 1.62
(P < 0.0001) for low fruit frequency, frequency, 0.70
X X
BMI was not significantly associated with depression scores (P < 0.0001) for low ready to eat food frequency, 0.73 (P < 0.05) for low snack food and 0.40 (P < 0.05) for low fast food frequency
Peltzer and Pengpid, 2017a [52] N/A CES-D FFQ ANCOVA, descriptive statistics Age, sex, subjective socio-economic status, country, BMI and PA Fruit consumption was negatively associated with depression. Unhealthy dietary behaviours were positively associated with depression Depression score was 13.28 for no fast food versus 13.70 for highest fast food consumption X
Peltzer and Pengpid, 2017b [53] N/A CES-D FFQ Stepwise multiple linear regression Fruit and vegetable consumption, socio-demographic and health-related factors Depression decreased with any increase in fruit and vegetable consumption Strongest decrease in depression was with six servings of fruit and vegetables,
b = −1.04 (P < 0.001)
X X
Smith-Marek et al., 2016 [54] N/A CES-D Three items taken from the Family Transitions Project survey Path analysis Trauma, diet and exercise A healthier diet was positively associated with lower depression scores b = 2.57
(P < 0.001)
X X
Breiholz, 2010 [120] N/A CES-D FFQ Independent samples t-test Gender There was no association between high consumption of fruits/vegetables and depression N/A
El Ansari et al 2014 [55] N/A BDI FFQ
(12 items)
Regression analyses University, sex Unhealthy food was positively correlated with depression scores (i) Fruit/vegetable intake was negatively correlated with depression scores (ii) (i) Coefficient = 
0.072 for female, 0.158 for male.
(ii) Coefficient = 
−0.081 for female, −0.115 for male
X X
Mikolajczyk et al., 2009 [59] N/A BDI FFQ Multivariable linear regression analysis Gender and country In females only, poor diet quality was positively associated with depression Estimates for change in BDI per unit of food group frequency scale was −1.69 (P = 0.002), −1.62, (P = 0.003), −1.47 (P = 0.003) for less frequent consumption of fruits, vegetables and meat respectively X X
Oleszko et al., 2019 [56] N/A BDI FFQ (for 30 days before study) Non-parametric Tau Kendall’s test N/A Diet quality was negatively associated with depression Tau Kendall’s = −0.09 (P < 0.01) X X
Rossa-Rocor et al., 2021 [49] DSQ PHQ-9 One item dietary preference Multivariate regression analysis Age, gender, ethnicity, PA, sleep, weight satisfaction, stress, stressful life events, social support The junk food component was positively associated with depression β = 0.26, P < 0.001 X X
Romijn, 2020 [57] N/A PHQ-9 FFQ Pearson’s correlation coefficients Gender, ethnicity, year of study, eating disorder Diet quality was negatively associated with depression Pearson’s coefficient = −0.38 (P < 0.001) X X
Rossa-
Roccor, 2019 [60]
N/A PHQ-9 Posteriori self-reported diet Multiple linear regression Social support, PA, stress, body image and stressful life events The processed food diet pattern was positively associated with depression scores (z-score β = 0.21, P ≤ .001). z-score β= 0.21 (P ≤ 0.001) X X
Jaalouk et al., 2019 [121] N/A PHQ-9 73-item FFQ Multivariable linear regression analyses Age, sex, income, PA, BMI, family history of mental illness, alcohol consumption, stressful life events, worrying about loss of control over how much they eat, use of antidepressants There was no association of identified dietary patterns (traditional Lebanese, Western fast food, dairy, Lebanese fast food, fruits) with depression scores N/A X
Tran et al., 2017 [61] N/A Clinical screening Dietary questionnaire  Multivariate logistic regression models Age, gender, blood pressure, heart rate, BMI, presence of depressive disorder, anxiety disorder and panic attack disorder Poor diet quality was associated with increased risk for depression OR 1.49 (P < 0.0001) X X
Wattick et al., 2018 [58] N/A Centre for Disease Control and Prevention’s Healthy Days Measure Dietary questionnaire Logistic regression Gender, housing and food security Fruit and vegetable intake were negatively associated with depression in males OR 0.68 (95% CI 0.50–0.89) X X
Mental health parameter: anxiety
Author, year Diet quality tool Anxiety tool Dietary assessment Model Adjustment Result OR, HR or RR, β coefficients, or other statistics Hypothesis outcome Effect sizea
1 2 3 Small Medium Large
Faghih et al., 2020 [46] DASH DASS-21 Semi-quantitative FFQ Pearson’s correlation coefficients Socio-economic, lifestyle, anthropometric characteristics Diet quality was negatively associated with anxiety scores Pearson’s correlation coefficient = −0.325 (P < 0.001) X X
Ramón-
Arbués et al., 2019 [64]
HEI DASS-21 N/A Pearson’s correlation coefficients Age, sex, study area, habitual residence, relationship status, height, weight, perceived economic situation, smoking, alcohol consumption, PA and sedentary lifestyle Diet quality was negatively associated with anxiety scores Pearson’s correlation coefficient = −0.10 (P < 0.01) X X
Attlee et al., 2022 [65] E-DII DASS-21 24-h dietary recall Logistic regression analysis Body habitus measures (BMI and WC), nutrient intakes and specific food groups, smoking status, PA categories Each point increase in the E-DII score was associated with symptoms of anxiety OR = 1.35; 95% CI: 1.07–1.69; P = 0.01 X X
Lee et al., 2022 [63] N/A DASS-21 FFQ Linear regression Age, gender, ethnicity, relationship status, employment, income, living arrangements, number of children, education The likelihood of more severe anxiety increased with higher consumption junk food β = 0.62, 95% CI: 0.01, 1.22 X X
Rossa-Rocor et al., 2021 [49] DSQ GAD-7 One item dietary preference Multivariate regression analysis Age, gender, ethnicity, PA, sleep, weight satisfaction, stress, stressful life events, social support The junk food component was positively associated with anxiety β = 0.18, P = 0.001 X X
Romijn, 2020 [57] N/A GAD-7 FFQ Pearson’s correlation coefficients Gender, ethnicity, year of study, eating disorder Diet quality was negatively correlated with anxiety scores Pearson’s correlation coefficient = −0.31 (P < 0.001) X X
Rossa-Roccor, 2019 [60] N/A GAD-7 Posteriori self-reported dietary patterns Multiple linear regression Social support, PA, stress, body image and stressful life events The processed food diet pattern was positively associated with anxiety β = 0.14 (P ≤ 0.001) X X
Wattick et al., 2018 [58] N/A Centre for Disease Control and Prevention Healthy Days Measure DSQ Logistic regression Gender, housing and food security Higher added sugars intake was positively associated with anxiety in females OR = 1.18 (95% CI 1.05–1.32) X X
Tran et al., 2017 [61] N/A Clinical screening Questionnaire about dietary behaviour  Multi variate logistic regression models Age, gender, blood pressure, heart rate, BMI, presence/absence of depressive disorder, anxiety disorder and panic attack disorder There was no association between bad dietary behaviour and anxiety. N/A X
Mental health parameter: stress
Author, year Diet quality tool Stress tool Dietary assessment Model Adjustment Result OR, HR or RR, β coefficients, or other statistics Hypothesis outcome Effect sizea
1 2 3 Small Medium Large
Faghih et al., 2020 [46] DASH DASS-21 Semi-quantitative FFQ Pearson’s correlation coefficients Socio-economic, lifestyle, anthropometric characteristics Diet quality was negatively correlated with stress score Pearson’s coefficient = −0.408 (P < 0.001) X X
Saharkhiz et al., 2021 [68] DASH score DASS-21 FFQ Multinomial logistic regression Age, BMI, energy intake Adherence to DASH style-pattern was associated with a lower stress score OR = 0.32; 95% CI: 0.14–0.71, P = 0.009; second tertile with first DASH tertile X X
Ramón-
Arbués et al., 2019 [64]
HEI DASS-21 N/A Pearson’s correlation coefficients Age, sex, study area, habitual residence, relationship status, height, weight, perceived economic situation, smoking, alcohol consumption, PA and sedentary lifestyle Diet quality was negatively correlated with stress score Pearson’s coefficient = −0.07 (P < 0.05) X X
Attlee et al., 2022 [65] E-DII DASS-21 24 h dietary recall Logistic regression analysis Body habitus measures (BMI and WC), nutrient intakes and specific food groups, smoking status, PA categories Each point increase in the E-DII score was associated with symptoms of stress. OR = 1.41; 95% CI: 1.12–1.77; p = 0.003 X X
Stanton et al., 2021 [62] N/A DASS-21 Previously validated Australian FFQ Multivariate regression analysis Gender, age, enrolment, ethnicity, relationship status, living arrangement, work, health conditions Intake of snack foods was associated with higher stress scores β = 3.92, P = 0.055 X X
Lee et al., 2022 [63] N/A DASS-21 FFQ Linear regression Age, gender, ethnicity, relationship status, employment, income, living arrangements, number of children, education The likelihood of more severe stress increased with lower consumption of dairy products β = −1.94, 95% CI, −3.65, −1.23 X X
Fabian et al., 2013 [122] Dietary guideline adherence index 27-item stress questionnaire FFQ Pearson’s chi-squared test Age, gender, household income, school, BMI Dietary patterns were not associated with stress levels N/A X
Alfreeh et al., 2020 [67] E-DII PSS-10 FFQ (Saudi) Multiple linear regression analyses Age, marital status, education level, course, income, financial status, sleep, PA, previous weight reduction diet Pro-inflammatory diets were associated with increased stress. A higher E-DII score per 1 SD (1.8) was associated with 2.4-times higher PSS score. 95% CI: 1.8, 3.1
Pearson’s partial correlation coefficient of the relationship between E-DII scores and PSS scores was (r) 0.46
X X
El Ansari et al., 2015a [66] Dietary guideline adherence index PSS 12-item FFQ Spearman rank coefficients Age, sex, living situation, economic situation, moderate PA and BMI Diet quality was negatively correlated to stress Males:
r = −0.21, P < 0.001
Females:
r = −0.13, P < 0.001
Normal weight:
r = −0.13, P < 0.001
Overweight:
r = −0.21, P = 0.002
X X
El Ansari et al., 2014 [55] N/A PSS 12-item FFQ Regression analyses University, sex Unhealthy foods were positively correlated with stress for females (i).
Fruits and vegetables were negatively correlated with stress (ii)
(i) Coefficient = 0.051
(ii) Coefficient = 
−0.067 for female,
−0.092 for male
X X
Liu et al., 2007 [51] N/A PSS FFQ Stepwise logistic regression Gender, grade, city, perceived weight, smoking level and alcohol use Low fruit frequency was positively correlated with stress (i).
Low ready to eat food frequency (ii) and low snack food frequency (iii) were negatively correlated with stress.
There was no association between BMI and stress scores
(i). OR = 1.53
(P < 0.01)
(ii) OR = 0.69
(P < 0.01)
(iii) OR = 0.75
(P < 0.05)
X X
Mikolajczyk et al., 2009 [59] N/A PSS 12-item FFQ Multivariable linear regression analysis Gender and country In females only,
consumption of sweets was positively associated with stress (i). In females only, consumption of fruits (ii) and vegetables (iii) was negatively associated with stress
(i) Estimate = 0.54
(P = 0.04)
(ii) Estimate = −1.17 (P < 0.001)
(iii) Estimate = −0.82 (P = 0.003)
X X
Lockhart, 2017 [123] N/A 5-item emotional distress scale FFQ Multiple linear regression Exercise and rest No correlation between consumption of fruits and vegetables and emotional distress N/A X
Mental health parameter: general mental well-being
Author, year Diet quality tool Mental well-being tool Dietary assessment Model Adjustment Result OR, HR or RR, β coefficients or other statistics Hypothesis outcome Effect sizea
1 2 3 Small Medium Large
Aceijas et al., 2017 [39] REAP-S SWEMWBS N/A Multivariate analysis Gender, lack of help-seeking behaviour in case of distress, negative attitudes towards nutrition-related activities, financial difficulties Low diet quality almost doubled the risk of low mental well-being OR = 1.7 (95% CI 1.0-2.7, P = 0 0.04). X X
Lo Moro et al., 2021 [71] MEDAS WEMWBS N/A Linear regression analysis Age, gender The mental well-being and adherence to MD were positively associated AdjB 0.676, 95% CI 0.277–1.075, P = 0.001 X X
El Ansari et al., 2015b [69] Dietary guideline adherence index Assessment of self-reported health complaints (22 items) 12-item FFQ Multi nomial logistic regression model Age group, living situation, economic situation, PA, BMI There was a negative correlation between diet quality and psychological health complaints Beta coefficient = 0.06 X X
Hendy, 2012 [70] Scores for total calories, carbohydrate percentage of calories, grams saturated fat and milligrams of sodium PANAS Anonymous 7-day record of foods Multiple regression analyses Restrained eating scores and gender Consumption of calories (i), saturated fat (ii) and sodium (iii) was significantly associated with increased negative affect. There was no association for carbohydrate consumption (i) b = 0.45
(ii) b = 0.43
(iii) b = 0.45
X X
Lopez-
Olivares, 2020 [72]
PRE-DIMED Questionnaire PANAS N/A Multiple regression models Age, sex, PA, general state of health   A strict adherence to the MD was positively associated with positive emotional state. There was no association with negative emotional state Coefficient = 0.018
(P = 0.009)
X X
Faghih et al., 2020 [46] DASH GHQ-12 Validated 168-item semi-quantitative FFQ Pearson’s correlation coefficient Socio-economic, lifestyle, anthropometric characteristics Diet quality was positively correlated with mental health well-being Pearson’s correlation coefficient = −0.431, (P < 0.001) X X
Mochi-
masu et al., 2016 [73]
N/A GHQ-12 FFQ Multiple regression analysis BMI, PAL, energy and sucrose Confectionaries intake was negatively associated with mental well-being and was the determining factor for the GHQ12 scores b = 0.160,
(P = 0.042)
X X
Knowlden et al., 2016 [74] N/A K-6 FFQ
(24 h)
Pearson’s correlation and Cronbach alphas Optimism, self-esteem and social support Frequent fruit consumption (i) and infrequent consumption of sugar-sweetened beverages (ii) was associated with low levels of mental distress.
No associations with BMI
(i) H2 = 7.268
(P = 0.026)
(ii) H2 = 18.15
(P < 0.001)
X X
Lesani et al., 2016 [75] N/A Oxford Happiness Questionnaire FFQ ANCOVA BMI, marital status, socio-economic status, PA, experience of stress in the last 6 months and having a defined disease Amount of fruit and vegetable consumption was positively associated with mental well-being P < 0.045 for 1 versus 3 servings per day X
Peltzer and Pengpid, 2017a [52] N/A SHS FFQ ANCOVA Age, sex, subjective socio-economic status, country, BMI and PA Diet quality was positively associated with happiness and high life satisfaction SHS score was 2.87 for no fruit consumption versus 3.03 for consuming three fruits per day X
Piqueras et al., 2011 [76] N/A SHS FFQ Multi variate binary logistic regression Gender, age, perceived stress and health behaviours Intake of fruits and vegetables intake was positively associated with happiness Adjusted OR = 1.34
(P = 0.000)
X X
Schnettler et al., 2015 [77] N/A SWLS SWFL
and FFQ
Dunnett’s T3 multiple comparisons test Sex, age, residence, socio-economic factors Students with healthful eating habits had higher levels of life satisfaction and satisfaction with food-related life The group ‘satisfied with their life and their food-related life’ had a higher percentage of fruit (41.7%) and vegetable (57.6%) consumption daily X
Rossa-
Rocor 2019 [60]
N/A QOL
Single item
Posteriori self-reported dietary patterns Multiple linear regression Social support, PA, stress, body image and stressful life events There was no association between diet preference categories and mental well-being N/A X
Mental health parameter: academic stress
Author, year Dietary score Academic stress tool Dietary assessment Model Adjustment Result OR, HR or RR, β coefficients or other statistics Hypothesis outcome Effect sizea
1 2 3 Small Medium Large
Chacon-Cuberos et al. 2019 [78] KIDMED Validated Scale of Academic Stress N/A Regression model Sex, BMI MD adherence decreased stress in ‘Communication of own idea’ for high versus low MD adherence F = 2.801
(P = 0.045)
X X
Mental health parameter: self-concept
Author, year Dietary score Self-concept tool Dietary assessment Model Adjustment Result OR, HR or RR, β coefficients or other statistics Hypothesis outcome Effect sizea
1 2 3 Small Medium Large
Chacon-Cuberos et al., 2018 [79] KIDMED AF-5 N/A Structural Equation Model, Pearson Chi-square test) Task and Ego Climate, Tobacco consumption, adherence to MD, PA, alcohol consumption, VO2MAX, Self-Concept, gender MD was positively associated with self-concept b = 0.08, (P < 0.05 for male)
b = 0.17, (P < 0.01) for female)
X X
Zurita-
Ortega et al., 2018 [80]
KIDMED AF-5 N/A Chi-square analysis and ANOVA MD, PA, gender, religious belief, university campus and place of residence Adherence to MD was positively associated with academic self-concept and physical self-concept.
There were no associations for social, emotional and family self-concept
Academic self-concept (P = 0.001) and physical self-concept (P = 0.005) were more positive with high MD adherence (M = 3.67 and M = 3.39 respectively) compared with medium adherence (M = 3.45 and M = 3.16 respectively) X
Mental health parameter: psychological resilience
Author, year Dietary score Psychological resilience tool Dietary assessment Model Adjustment Result OR, HR or RR, β coefficients or other statistics Hypothesis outcome Effect sizea
1 2 3 Small Medium Large
Lutz et al., 2017 [81] HEI CDRS The Block FFQ Logistic regression Race, ethnicity, education, smoking, age, BMI, sex and military branch Higher diet quality was associated with an increased likelihood of a participant being in the high-resilience group OR 1.02
(95% CI 1.01–1.04)
X X
Mental health parameter: PTSD
Author, year Dietary score PTSD tool Dietary assessment Model Adjustment Result OR, HR or RR, β coefficients or other statistics Hypothesis outcome Effect sizea
1 2 3 Small Medium Large
Peltzer and Pengpid, 2017a [52] N/A B7ISQ Food frequency questionnaire (FFQ) ANCOVA Age, sex, subjective socio-economic status, country, BMI and PA Fruit consumption were negatively associated with traumatic stress symptoms B7ISQ scores were 19.25 for consumption of 4 or more fruits versus
19.91 for no fruit consumption
X
Smith-
Marek et al., 2016 [54]
N/A PCL-5 Three items taken from the Family Transitions Project survey Path analysis Trauma, diet and exercise A healthier diet was significantly associated with lower post-traumatic stress scores b = 1.60
(P < 0.01)
X X

Note: Studies ordered according to diet quality tool used; if no diet quality tool used, studies were ordered according to depression tool.

Dietary measures: Diet inflammatory score (DII), Dietary Approaches to Stop Hypertension score (DASH), Energy-adjusted Dietary Inflammatory Index (E-DII), Healthy eating index (HEI), Diet quality score (DQS), Food frequency questionnaire (FFQ), Ecological Momentary Assessment (EMA), Dietary Screener Questionnaire (DSQ), Rapid Eating and Activity Assessment for Patients-Short Version (REAP-S), PREvención con DIeta MEDiterránea questionnaire (PREDIMED), Satisfaction with Food-related Life Scale (SWFL), Test of Adherence to Mediterranean Diet (KIDMED), Mediterranean diet (MD), Physical Activity (PA), Body Mass Index (BMI).

Mental health scores: Zung Self-Rating Depression Scale (ZSRDS), Positive and Negative Affect Scale (PANAS), Depression, anxiety and stress scale (DASS-21), Beck Depression Inventory (BDI), Centre for Epidemiologic Studies Depression Scale (CES-D), Patient health questionnaire (PHQ-9), Cohen’s Perceived Stress Scale (PSS), General anxiety disorder 7 (GAD-7), Warwick–Edinburgh Mental Wellbeing Scale short version (SWEMWBS), Positive and Negative Affect Scale (PANAS), 12-item general health questionnaire (GHQ-12), Kessler-6 Psychological Distress Scale (K-6), Subjective happiness scale (SHS), Satisfaction with Life Scale (SWLS), Connor-Davidson Resilience Scale (CDRS), Breslau’s 7-item screening questionnaire (B7ISQ), Post-traumatic stress Checklist (PCL-5), Five-Factor Self-Concept Questionnaire (AF-5).

Statistics: Odds Ratio (OR), Hazard Ratio (HR), Relative Risk (RR), Confidence Interval (CI), Standard Error (SE), Analysis of covariance (ANCOVA), Between group differences (H2), Mean (M), Regression coefficient (F).

Not applicable (N/A).

Hypothesis: Good diet quality will have a beneficial effect on mental health parameters, and/or bad diet quality will have a detrimental effect on mental health parameters.

Hypothesis outcomes:

(i) Hypothesis accepted.

(ii) Hypothesis rejected—good diet quality had an adverse effect on mental health.

(iii) Hypothesis rejected—no association between diet quality and mental health.

a

If applicable.