Table 1.

Human retina patients’ samples information, including gender, age, diabetes (Yes or No), cause of death, application of the samples, time elapsed since donor death and retina culture, eye complications status and comments regarding the presence/absence of diagnosed diabetic retinopathy.

Age	Gender	Diabetes	Ethnicity	Cause of death	Application	Time elapsed before culture (h)	Eye complication Status	Diabetes status and other diagnosis
64	Male	YES	Unknown	Heart failure	Retina and retina EVs proteomic analysis and WB	32	Diabetic Retinopathy	DM Type I
63	Male	YES	Unknown	Renal failure	Retina and retina EVs proteomic analysis and WB	24	Diabetic Retinopathy	DM Type I
54	Male	YES	Hispanic	Coronary Artery Disease	Retina EVs isolation for NTA, Uptake and TEM	22	No Diabetic Retinopathy	Morbidly obese. DM Type II
73	Male	YES	Caucasian	Hypoglicemia	Retina EVs isolation for NTA, Uptake and WB	21	Diabetic Retinopathy	Cataracts, Possible Glaucoma
71	Male	YES	Unknown	Pancreatic cancer	Retina EVs isolation for NTA	24	Diabetic Retinopathy	Cataracts
68	Male	YES	Hispanic	unknown	Retina EVs isolation for NTA and WB	16	No Diabetic Retinopathy	Cataracts, Lasik
68	Male	YES	Hispanic	Cardiopulmonary collapse	Retina EVs isolation for NTA and WB	15	No Diabetic Retinopathy	Cataracts, Lasik
66	Female	YES	Hispanic	unknown	Retina EVs isolation for NTA and WB	22	Diabetic Retinopathy	Cataracts, Lasik
59	Male	YES	Caucasian	Heart disease	Retina EVs isolation for NTA and WB	24	No Diabetic Retinopathy	Hydrocephalus
65,1 ± 5,9						22,2 ± 4,9
62	Male	NO	Unknown	Heart failure	Retina and retina EVs proteomic analysis and WB	26	Non Diabetic - No DR	Metastatic cancer
56	Male	NO	Unknown	Unknown	Retina and retina EVs proteomic analysis and WB	13	Non Diabetic - No DR	None
26	Male	NO	Caucasian	Heart failure	Retina EVs isolation for NTA and qPCR	40	Non Diabetic - No DR	Drug overdose. No ocular history
27	Male	NO	Unknown	Cholangiocarcinoma stage IV	Retina EVs isolation for WB	12	Non Diabetic - No DR	Artificial tears
35	Male	NO	Causcasian	Endocarditis	Retina EVs isolation for NTA and WB	44	Non Diabetic - No DR	None
21	Male	NO	Caucasian	Lupus	Retina EVs isolation for NTA and WB	20	Non Diabetic - No DR	None
32	Male	NO	Caucasian	Sheptic shock	Retina EVs isolation for NTA	29	Non Diabetic - No DR	None
63	Male	NO	Hispanic	Cardiopulmonary Arrest	Retina EVs isolation for NTA	25	Non Diabetic - No DR	Colorectal cancer
31	Male	NO	Caucasian	Endstage Liver disease	Retina EVs isolation for NTA	48	Non Diabetic - No DR	None
61	Female	NO	Caucasian	Amyotrophic lateral sclerosis	Retina EVs isolation for NTA	36	Non Diabetic - No DR	None
52	Female	NO	Caucasian	Cerebrovascular/Stroke	Retina EVs isolation for NTA	87	Non Diabetic - No DR	None
39,1 ± 16,2						37,8 ± 21,7

Average ± standard dev. Included below age and time elapsed columns. EVs, Extracellular vesicles; WB, Western Blot; NTA, Nanoparticle tracking analysis; TEM, Transmission electron microscopy; DM, Diabetes Mellitus; DR, Diabetic Retinopathy.