Table 3.
GSEA pathways up-regulated and down-regulated due to DR1 group
| Gene sets | SIZE | NES | NOM p-val | FDR q-val |
|---|---|---|---|---|
| Up-regulated gene sets in DR1 group | ||||
| HALLMARK_COAGULATION | 133 | 2.17 | 0.000 | 0.000 |
| HALLMARK_IL2_STAT5_SIGNALING | 197 | 1.81 | 0.000 | 0.122 |
| HALLMARK_ANGIOGENESIS | 36 | 1.69 | 0.000 | 0.135 |
| HALLMARK_IL6_JAK_STAT3_SIGNALING | 83 | 1.68 | 0.000 | 0.116 |
| HALLMARK_INFLAMMATORY_RESPONSE | 198 | 1.68 | 0.000 | 0.102 |
| HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 198 | 1.68 | 0.000 | 0.090 |
| HALLMARK_KRAS_SIGNALING_UP | 194 | 1.58 | 0.000 | 0.130 |
| HALLMARK_ALLOGRAFT_REJECTION | 195 | 1.54 | 0.000 | 0.118 |
| HALLMARK_INTERFERON_GAMMA_RESPONSE | 194 | 1.47 | 0.000 | 0.135 |
| HALLMARK_APICAL_SURFACE | 44 | 1.44 | 0.000 | 0.150 |
| HALLMARK_INTERFERON_ALPHA_RESPONSE | 95 | 1.37 | 0.000 | 0.173 |
| Down-regulated gene sets in the DR1 group | ||||
| HALLMARK_PANCREAS_BETA_CELLS | 40 | −1.67 | 0.000 | 0.187 |
| HALLMARK_SPERMATOGENESIS | 131 | − 1.46 | 0.000 | 0.211 |