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. 2023 Jan 20;21(1):e07704. doi: 10.2903/j.efsa.2023.7704

Reference

Study

Country

Design

N randomised/completed

Duration(a)

Recruitment criteria

Subject characteristics at baseline(b) Intervention(b) Outcomes assessed Results(b)

Navas‐Carretero et al. (2011)

Spain

RCT

G1, non‐enriched chicken breast: 16/13

G2, Se‐enriched chicken breast: 16/11

Duration: 10 wk

Aged 20–45 yr; BMI 18.5–30 kg/m2; not taking any medication or following any dietary treatment; had maintained their weight (±3 kg) for the last 3 mo; no diabetes, thyroid impairments, or other endocrine disturbances; not suffering gastric and peptic ulcer problems; no hypertension, constipation, or diarrhoea.

Sex: M and F

Age (yr): 20–45

BMI (kg/m 2 )

G1: 24.2 ± 2.1

G2: 24.1 ± 2.7

Ethnicity: NR

Blood Se (μg/dL)

G1: 14.2 ± 1.4

G2: 14.6 ± 1.7

Blood pressure (mmHg)

Se intake: NR

Non‐enriched chicken breast

vs 22 μg/d Se supplementation as Se‐enriched chicken breast

Isocaloric diet with 30% of energy as proteins

Blood Se, end of trial (μg/dL):

G1: 0.7 ± 0.9

G2: 0.2 ± 1.4

SBP and DBP (method not described; not a pre‐planned outcome)

Baseline

SBP (mmHg)

G1: 110.0 ± 7.4

G2: 110.0 ± 12.0

DBP (mmHg)

G1: 68.8 ± 6.8

G2: 69.1 ± 8.6

Changes from baseline

SBP (mmHg)

G1: −8.5 ± 10.3

G2: −1.8 ± 8.7

G1 vs G2 NS

DBP (mmHg)

G1: −1.1 ± 8.9

G2: −3.2 ± 7.5

G1 vs G2 NS

d: day; DBP: diastolic blood pressure; F: females; Gx: group x; M: males; mo: month; NR: not reported; SBP: systolic blood pressure; SD: standard deviation; Se: selenium; RCT: randomised controlled trial; wk: week; yr: year.

(a) Duration = duration of the treatment phase, unless specified otherwise.

(b) Mean ± SD, unless specified otherwise.