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Diagram showing the deleterious impact of juglone implication on bovine oocyte during IVM. Juglone interact with the PI3K/AKT/mTOR signaling and the underlying cascades regulated by this pathway, the effects that negatively retard the development and quality of exposed oocyte. Red and green dots indicate the decrease and increase in the cellular processes affected by juglone in bovine matured oocyte, respectively.
