. 2023 Jan 12;13(2):262. doi: 10.3390/ani13020262

Table 3.

Effects of NAC administration on redox status in piglets infected with PEDV.

Items	−PEDV		+PEDV		SEM	p-Value
Items	−NAC	+NAC	−NAC	+NAC	SEM	PEDV	NAC	PEDV × NAC
CAT (U/mg prot)
Gastrocnemius	7.28 ^a	9.43 ^b	9.26 ^b	12.73 ^c	0.82	<0.001	<0.001	<0.001
Lung	25.15	23.68	12.34	14.89	1.99	<0.001	0.71	0.16
Lymph node	16.43 ^c	11.39 ^b	4.42 ^a	5.09 ^a	1.53	<0.001	0.07	<0.001
Spleen	13.32 ^a	20.17 ^b	28.02 ^c	19.73 ^b	2.24	<0.001	0.61	<0.001
Liver	67.35	96.62	58.76	111.59	10.51	0.71	<0.001	0.18
MPO (U/g prot)
Gastrocnemius	0.16	0.18	0.21	0.21	0.01	0.27	0.09	0.02
Lung	0.35	0.37	0.42	0.41	0.02	0.11	0.94	0.41
Lymph node	0.48 ^a	0.59 ^a	0.643 ^a	1.35 ^b	0.12	<0.001	<0.001	<0.001
Spleen	11.29 ^b	1.06 ^a	1.77 ^a	1.61 ^a	1.34	<0.001	<0.001	<0.001
Liver	0.22	0.26	0.19	0.22	0.02	0.10	0.15	0.61
SOD (U/mg prot)
Gastrocnemius	216.86	207.29	212.46	207.03	8.13	0.35	0.772	0.79
Lung	101.87	93.77	105.88	102.89	4.85	0.18	0.26	0.61
Lymph node	184.86 ^c	145.35 ^ab	135.30 ^a	173.16 ^bc	12.48	0.271	0.93	<0.001
Spleen	152.96	148.81	116.01	83.95	12.01	<0.001	0.04	0.11
Liver	57.49	61.02	46.89	58.85	4.71	0.21	0.13	0.41
GSH-Px (U/mg prot)
Gastrocnemius	0.09 ^b	0.05 ^a	0.05 ^a	0.10 ^b	0.01	0.2	0.62	<0.001
Lung	91.46	91.66	114.19	127.05	7.28	<0.001	0.31	0.32
Lymph node	207.401 ^ab	178.67 ^a	198.04 ^ab	231.20 ^b	14.08	0.07	0.85	0.01
Spleen	229.07	187.69	128.6	126.71	16.35	<0.001	0.05	0.07
Liver	22.14	20.89	22.34	23.91	2.06	0.41	0.93	0.47
H₂O₂ (mol/mg prot)
Gastrocnemius	15.99	14.36	13.94	15.51	1.33	0.71	0.97	0.19
Lung	45.31 ^a	43.83 ^a	47.95 ^a	29.82 ^b	3.97	0.01	0.11	0.02
Lymph node	3.36 ^ab	3.48 ^bc	2.64 ^a	4.27 ^c	0.34	0.89	0.01	0.01
Spleen	85.92	76.55	49.83	62.31	7.01	<0.001	0.77	0.05
Liver	21.23	27.81	22.84	22.16	3.36	0.51	0.33	0.23
MDA (nmol/mg prot)
Gastrocnemius	0.61 ^a	0.51 ^a	0.66 ^a	1.42 ^b	0.13	<0.001	<0.001	<0.001
Lung	3.21	2.26	2.35	1.36	0.22	<0.001	<0.001	0.91
Lymph node	2.73	2.13	2.11	1.85	0.19	0.01	0.01	0.31
Spleen	4.15	3.84	4.78	4.17	0.34	0.127	0.15	0.62
Liver	0.98	1.17	2.11	1.23	0.19	0.05	0.11	0.16

Values are mean and pooled SEM, n = 8; CAT = catalase; MPO = myeloperoxidase; GSH-Px = glutathione peroxidase; H₂O₂ = hydrogen peroxide; MDA = malondialdehyde; ^a,b,c Within a row, means with different superscripts differ, p < 0.05.