Table 6.
Effects of NAC administration on mRNA expression levels of TRPV6 and KCNJ13 in the liver, spleen, lung, lymph node, and gastrocnemius muscle in piglets infected with PEDV.
| Items | −PEDV | +PEDV | SEM | p-Value | ||||
|---|---|---|---|---|---|---|---|---|
| −NAC | +NAC | −NAC | +NAC | PEDV | NAC | PEDV × NAC | ||
| TRPV6 | ||||||||
| Liver | 1.00 b | 1.27 a | 0.90 b | 0.56 c | 0.07 | <0.001 | 0.60 | <0.001 |
| Lung | 1.00 b | 1.59 a | 1.02 b | 1.01 b | 0.08 | <0.001 | <0.001 | <0.001 |
| Spleen | 1.00 | 1.04 | 0.85 | 0.95 | 0.08 | 0.14 | 0.42 | 0.71 |
| Lymph node | 1.00 | 1.49 | 1.17 | 1.34 | 0.10 | 0.91 | <0.001 | 0.13 |
| Gastrocnemius | 1.00 | 1.04 | 1.85 | 2.06 | 0.12 | <0.001 | 0.28 | 0.46 |
| KCNJ13 | ||||||||
| Liver | 1.00 b | 1.83 a | 1.15 b | 0.62 c | 0.08 | <0.001 | 0.07 | <0.001 |
| Lung | 1.00 | 1.03 | 1.16 | 0.97 | 0.08 | 0.51 | 0.30 | 0.16 |
| Spleen | 1.00 | 1.11 | 1.17 | 1.50 | 0.09 | <0.001 | 0.02 | 0.23 |
| Lymph node | 1.00 | 1.52 | 1.39 | 1.70 | 0.09 | <0.001 | <0.001 | 0.26 |
| Gastrocnemius | 1.00 b | 0.94 b | 0.99 b | 1.38 a | 0.09 | 0.02 | 0.07 | 0.02 |
Values are mean and pooled SEM, n = 8; a,b,c within a row, means with different superscripts differ, p < 0.05.