. 2023 Jan 12;13(2):262. doi: 10.3390/ani13020262

Table 7.

Effects of NAC administration on the mRNA expression of IL-1β, IL-4, IL-10, TNF-α, and S100A12 in liver, spleen, lung, lymph node, and gastrocnemius muscle in piglets infected with PEDV.

Items	−PEDV		+PEDV		SEM	p-Value
Items	−NAC	+NAC	−NAC	+NAC	SEM	PEDV	NAC	PEDV × NAC
IL-1β
Liver	1.00 ^b	1.34 ^a	0.90 ^b	0.80 ^b	0.07	<0.001	0.12	0.01
Spleen	1.00 ^a	0.68 ^b	0.73 ^b	0.79 ^b	0.06	0.14	0.03	<0.001
Lymph node	1.00 ^b	1.54 ^a	0.67 ^c	0.53 ^c	0.07	<0.001	0.01	<0.001
Gastrocnemius	1.00 ^a	0.64 ^b	0.59 ^b	0.72 ^b	0.05	<0.001	0.02	<0.001
IL-4
Lung	1.00 ^b	1.61 ^a	0.90 ^b	1.05 ^b	0.06	<0.001	<0.001	<0.001
Lymph node	1.00 ^a	0.79 ^b	0.18 ^d	0.48 ^c	0.05	<0.001	0.41	<0.001
IL-10
Liver	1.00	1.24	0.85	0.89	0.08	<0.001	0.09	0.23
Lung	1.00	1.20	0.85	1.01	0.08	0.04	0.03	0.78
Spleen	1.00 ^a	0.75 ^b	0.41 ^c	0.87 ^ab	0.06	<0.001	0.10	<0.001
Lymph node	1.00	0.92	1.46	1.21	0.09	<0.001	0.08	0.36
Gastrocnemius	1.00 ^a	0.68 ^b	0.76 ^b	0.83 ^ab	0.06	0.46	0.06	<0.001
TNF-α
Liver	1.00 ^b	1.28 ^a	0.57 ^c	0.59 ^c	0.06	<0.001	0.02	0.05
Lung	1.00 ^ab	1.21 ^a	1.07 ^ab	0.95 ^b	0.08	0.27	0.59	0.05
Spleen	1.00 ^a	0.46 ^b	0.41 ^b	1.01 ^a	0.06	0.72	0.61	<0.001
Lymph node	1.00	1.24	0.91	1.04	0.08	0.07	0.02	0.47
Gastrocnemius	1.00	0.82	0.79	0.61	0.06	<0.001	0.01	0.98
S100A12
Liver	1.00 ^b	1.39 ^a	1.39 ^a	1.11 ^b	0.09	0.54	0.57	<0.001
Lung	1.00 ^b	1.38 ^a	1.11 ^b	1.09 ^b	0.08	0.27	0.03	0.02
Spleen	1.00 ^a	0.68 ^b	0.54 ^b	0.97 ^a	0.06	0.19	0.40	<0.001
Lymph node	1.00	0.67	1.61	0.91	0.09	<0.001	<0.001	0.04
Gastrocnemius	1.00	0.63	0.90	0.60	0.06	0.30	<0.001	0.60

Values are mean and pooled SEM, n = 8; ^a,b,c,d Within a row, means with different superscripts differ, p < 0.05.