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. 2023 Jan 5;12(1):133. doi: 10.3390/antiox12010133

Figure 2.

Figure 2

Febuxostat ameliorates obesity in ovariectomized (OVX) mice. Sham-operated or ovariectomized (OVX) mice were treated for seven weeks with or without oral administration of Febu. (A) Representative micro-CT images of sham-operated and OVX mice with or without Febu treatment are shown. (B) Quantitative analysis of the abdominal fat from 1st to 6th lumbar vertebrae. n = 5 per group. Results are expressed as the mean ± SD. * p < 0.05. (C) Percent increase in body weight from the baseline in sham-operated and OVX mice with or without Febu treatment is shown. n = 5 per group. Results are expressed as the mean ± SD. * p < 0.05. vs. OVX at the indicated time point. (D) Representative images of H&E staining of the visceral white adipose tissue. Original magnification, ×200. Bar, 100 μm. (E) The area of adipocytes was measured. n = 5 per group. Results are expressed as the mean ± SD. * p < 0.05.