Table 1.
Analysis of pH, lactate and glucose in cell medium at different time points during different seeding conditions. Values are provided as means with standard deviation (SD) from independent triplicates. Reference values for venous blood, as prospectively perfused through the BHL, are in brackets [30]. RA1: rotational axis 1, RA2: rotational axis 2, MExch: medium exchange.
| pH (7.30–7.43) | Lactate (0.4–2.2 mmol/L) | Glucose (3.1–5.5 mmol/L) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Time [h] | |||||||||
| Seeding Condtionss |
T0 | T6 | T24 | T0 | T6 | T24 | T0 | T6 | T24 |
| 6 h, RA1 | 7.40 ± 0.01 | 7.13 ± 0.02 | _ | 0.57 ± 0.05 | 2.90 ± 0.08 | _ | 5.37 ± 0.05 | 4.37 ± 0.05 | _ |
| 6 h, RA2 | 7.43 ± 0.06 | 7.02 ± 0.02 | _ | 0.50 ± 0.08 | 3.83 ± 0.05 | _ | 5.30 ± 0.00 | 4.30 ± 0.08 | _ |
| 24 h, RA1 | 7.36 ± 0.04 | _ | 6.78 ± 0.02 | 0.50 ± 0.00 | _ | 8.30 ± 0.14 | 5.30 ± 0.00 | _ | 1.97 ± 0.05 |
| 24 h, RA2 | 7.35 ± 0.01 | _ | 6.71 ± 0.02 | 0.40 ± 0.00 | _ | 8.57 ± 0.71 | 5.17 ± 0.05 | _ | 1.63 ± 0.26 |
| 24 h, RA2, MExch | 7.33 ± 0.01 | 7.03 ± 0.01 | 6.94 ± 0.05 | 0.57 ± 0.05 | 3.53 ± 0.24 | 3.47 ± 0.48 | 5.10 ± 0.00 | 4.07 ± 0.09 | 4.17 ± 0.12 |