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Baicalein inhibited IRP1 activation and iron accumulation in the substantia nigra of rotenone-induced PD rats. (A) Iron content in the substantia nigra. (B) Aconitase activity. (C–G) ACO1(and IRP1) and its iron-regulating downstream proteins FPN1, DMT1, and TfR1. All data are presented as Mean ± SEM, n = 3. ## p < 0.01 vs. control; * p < 0.05, ** p < 0.01 vs. model.
