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. 2023 Jan 16;12(1):181. doi: 10.3390/antibiotics12010181

Table 11.

Rhein content, total phenolic content, antioxidant activity, anti-inflammatory activity and antibacterial activity against S. aureus of rhein-rich extract and its de-chlorophyll extracts.

Samples Rhein Content
(mg/g Extract)
Total Phenolic Content
(mg GAE/g Extract)
Scavenging Activity against DPPH, SC50 FRAP Value
(mg AAE/g Extract)
Albumin Denaturation Activity, IC50 (mg/mL) MIC (mg/mL)
Rhein-rich extract 10.36 ± 0.27 e 105.75 ± 0.97 c 1.25 ± 0.12 mg/mL c,d 112.35 ± 1.87 c 1.81 ± 0.03 b 0.625
De-chlorophyll extract with various decolorizing agents
  Palm oil 1.50 ± 0.10 b 107.30 ± 3.46 d 1.17 ± 0.08 mg/mL c 124.59 ± 1.96 d 2.51 ± 0.04 d 2.5
  Coconut oil 1.42 ± 0.09 a 120.43 ± 2.01 e 1.01 ± 0.12 mg/mL b 156.65 ± 3.57 e 2.64 ± 0.03 e 2.5
  Aluminum oxide 7.98 ± 0.02 c 27.26 ± 0.38 a 1.43 ± 0.07 mg/mL d 44.34 ± 1.58 b 2.01 ± 0.05 c 1.25
  Activated charcoal 8.52 ± 0.08 d 34.97 ± 5.91 b 1.69 ± 0.10 mg/mL e 38.29 ± 0.18 a 1.94 ± 0.04 b, c 1.25
Ascorbic acid n/a n/a 15.06 ± 0.37 µg/mL a n/a n/a n/a
Diclofenac diethylamine n/a n/a n/a n/a 1.04 ± 0.09 a n/a
Neomycin sulfate n/a n/a n/a n/a n/a 0.0625

Values expressed as mean ± SD. Different letters in the same column represent statistically significant differences with a confidence interval of 95% (p < 0.05). n/a: not applicable.