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. 2001 Jul;69(7):4667–4672. doi: 10.1128/IAI.69.7.4667-4672.2001

FIG. 2.

FIG. 2

Serum antibody titers following infection or immunization with chlamydia-pulsed DC. Sera were collected from naive mice, infected mice (35 days postinfection), and 14 days following two immunizations (administered 14 days apart) with chlamydia-pulsed DC (DC + HK EB) by i.v. and i.p. injection. Chlamydia-specific IgG1 and IgG2a titers were determined by ELISA. Naive mice did not elicit a chlamydia-specific IgG1 or IgG2a response. Infected mice elicited a predominantly IgG2a response. All mice immunized with chlamydia-pulsed DC by i.v. injection elicited a strong chlamydia-specific IgG2a and IgG1 response with higher titers than did mice that had been infected and resolved infection for 35 days. Three of the five mice immunized by i.p. injection elicited a chlamydia-specific IgG2a response. Ovals represent individual mice (solid ovals, IgG2a; open ovals, IgG1). Solid horizontal bars indicate the mean absorbance. Absorbance is shown on the y axis; 1:256 dilution of all sera is indicated on the x axis.