Figure 2.

Elevated plus maze test shows that SMFs could improve the exploration activity of aged mice. (A) The mice body weight changes; (B) food consumption; (C) water consumption; (D) representative trajectories of mice in elevated plus maze test at 56 and 61 weeks old, respectively. The blue and red points show start and end points, respectively; (E) time in the open arms; (F) total traveled distance; (G) total average velocity. n=8 mice for the sham, upward SMF or downward SMF group in the beginning of the experiment. Values were expressed as means ± SEM. * p < 0.05 by Student’s t-test. ns, no significance.