Table 1.
Screening of the inhibition potency of the curcuminoids (curcumin and DMC) and the curcumin analogues against hGSTP1-1 isoenzyme.
| Compound Code | Molecular Weight | Enzyme Inhibition (%) |
|---|---|---|
| Curcumin | 368.38 | 53.00 ± 1.98 |
| DMC | 338.35 | 94.56 ± 0.25 |
| DM15 | 274.36 | 66.23 ± 2.57 |
| DM46 | 334.40 | 8.50 ± 2.13 |
| DM57 | 394.46 | 16.75 ± 3.61 |
| DM62 | 310.34 | 8.40 ± 0.36 |
| DM95 | 354.39 | 44.18 ± 3.06 |
| DM96 | 266.29 | 86.99 ± 1.88 |
| DM100 | 366.41 | 40.00 ± 1.84 |
| DM101 | 326.34 | 72.28 ± 1.91 |
| DM109 | 270.27 | 79.06 ± 2.54 |
| DM148 | 298.29 | 54.80 ± 0.52 |
| DM151 | 338.35 | 88.18 ± 3.65 |