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. 2022 Dec 30;12(1):90. doi: 10.3390/antiox12010090

Figure 2.

Figure 2

Effect of PAC on glucose homoeostasis and insulin resistance. After 8-week diet, mice were submitted to an intra-peritoneal (A,B) insulin tolerance test (ipITT) following a 6 h fast. At week 10, mice were then submitted to an (C,D) oral glucose tolerance test (OGTT) following an overnight fast to evaluate (E,F) insulinemia. (G) The Homeostatic model assessment of insulin resistance (HOMA-IR) was calculated as described in Materials and Methods. Results are presented as mean ± SEM for n = 12–16 mice/group. * p < 0.05, *** p < 0.001 vs. chows; ## p < 0.01, ### p < 0.001 vs. HFHS mice.