Figure 8.

PACs modulate glucose metabolism in liver HFHS-fed mice. Protein mass of (A) G6Pase, (B) PEPCK as well as the transcriptional factor (C) ChREBP was assessed by Western blot as described in Materials and Methods. Data are expressed as the mean ± SEM for n = 4–7 mice/group with a representative gel per experiment. * p < 0.05, *** p < 0.001 vs. HFHS mice. Each set of experiments, including the proteins of interest and their β-actin (as a reference protein and a loading housekeeping control) was run on the same gel. G6Pase: Glucose 6-phosphatase; PEPCK: Phosphoenolpyruvate carboxykinase; ChREBP: Carbohydrate response element binding protein.