Table 6.
Binding energies resulting from molecular docking experiments of the selected compounds in the extracts of Cladonia, together with the standard inhibitor zileuton on 5-lipoxygenase (5-LOX).
Compound | Binding Energy (Kcal/mol) 5-Lipoxygenase (5-LOX) |
---|---|
Thamnolic acid | −7.40 |
13D acid | −5.60 |
Perlatolic acid | −7.10 |
Psoromic acid | −8.30 |
Orsellinic acid | −5.60 |
Atranorin | −7.20 |
Cetraric acid | −7.60 |
Squamatic acid | −7.60 |
Methylorsellinate | −5.40 |
Zileuton | −8.70 |