Table 2.
Characteristics of the 16 ESBL-producing E. coli isolates recovered from the fecal samples of healthy humans.
| Strain | Resistance Profile to Non Beta-Lactams | Beta-Lactamases | MLST | Phylogroup | PFGE | Class 1 Integron | Other Resistance Genes Detected Outside Integron |
|
|---|---|---|---|---|---|---|---|---|
| IntI1/ qacEΔ1 + sul1 |
Gene Cassette Arrangement | |||||||
| 3i | CIP, NAL, SXT, SUL, S, TET | CTX-M-15 | ND | A | P1 | +/+ | aadA1 | sul2, sul3, tetA |
| 5c | CIP, NAL, SUL, TET | CTX-M-1 | ST131 | B2 | P2 | −/− | - | sul2, tetA |
| 13c | NAL, SUL, S, GN, CHL | CTX-M-1 | ST1158 | D | P3 | −/− | - | sul2 |
| 19c | SXT, SUL, S, TET | CTX-M-15 | ST925 | D | P4 | −/− | - | sul2, tetA |
| 25c | CIP, NAL, SXT, SUL, AK, K, T, S, GN, CHL, TET | CTX-M-15, TEM-1 | ST5100 | A | P5 | +/+ | dfrA12-orf-aadA2 | sul1, sul2, tetB |
| 26c | SUL, TET | CTX-M-15 | ND | A | P6 | −/− | - | - |
| 30c | SXT, SUL, S, TET | CTX-M-27 | ST2887 | D | P7 | −/− | - | sul1, sul2, tetA |
| 32c | SXT, SUL, S, RAM, CHL | CTX-M-15 | ND | A | P8 | −/− | - | sul3 |
| 35c | SXT, SUL, S, TET | CTX-M-27 | ND | D | P9 | −/− | - | sul2, sul3, tetA |
| 37c | SXT, SUL | CTX-M-15 | ND | A | P10 | +/+ | dfrA5 | sul2, tetA |
| 39c | SXT, SUL, S, TET | CTX-M-15 | ND | A | P11 | −/− | - | sul2, tetA |
| 42c | SXT, SUL, S, TET | CTX-M-15, TEM-1 | ND | A | P12 | +/+ | dfrA12-orf-aadA2 | sul2, tetA |
| 45c | SUL, K, S, TET | CTX-M-27 | ND | D | P13 | −/− | - | sul2, tetA |
| 46c | CIP, NAL, SXT, SUL, K, T, S, GN, CHL, TET | CTX-M-55 | ST744 | D | P14 | +/+ | dfrA17-aadA5 | sul2, tetA |
| 47c | CIP, NAL, SXT, SUL, S, TET | CTX-M-15 | ND | A | P15 | −/− | - | sul2 |
| 49c | CIP, NAL, SXT, SUL, S, TET | CTX-M-1, TEM1 | St7366 | A | P16 | +/+ | dfrA5 | sul2, tetA |
SXT: trimethoprim–sulfamethoxazole; SUL: sulphonamides; AK: amikacine; K: kanamycine; T: tobramycine, S: streptomycin, GN: gentamicin, TET: tetracycline; CHL: chloramphenicol; NAL: nalidixic acid; CIP: ciprofloxacin; ND: not done.