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. 2022 Dec 22;12(1):15. doi: 10.3390/antibiotics12010015

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Structures of complexes of CAM-C5-BER and CAM-C8-BER with the T. thermophilus ribosome obtained by molecular docking. (A,B) Structures of CAM-C5-BER ((A), purple), CAM-C8-BER ((B), orange), and fMKFAI-NH-tRNA^Met (blue) docked into the crystal structure of T. thermophilus ribosome (PDB ID: 8CVL [76], light blue). (C,D) Superposition of the structures of CAM-C5-BER ((C), purple) and CAM-C8-BER ((D), orange) in complex with T. thermophilus ribosome carrying fMKFAI-NH-tRNA^Met (blue) obtained by molecular docking with the previously reported crystal structure of CHL (yellow) and P-site MAI-ACCA (yellow) in complex with T. thermophilus ribosome (PDB ID: 7RQE [16]). E. coli numbering of nucleotides is presented.