Table 1.
Suppression of the growth of E. coli and B. subtilis strains, including CHL-resistant ones, by CAM-C8-BER. CH3-C8-BER and CHL were used as controls. The values of a minimal inhibitory concentration (MIC, µM) are shown 1.
| E. coli K12 | E. coli JW5503 ΔtolC | E. coli JW5503 ΔtolC-CAT | B. subtilis 168 | B. subtilis-CAT 168 | |
|---|---|---|---|---|---|
| CAM-C8-BER | >100 | 12.5 | 50 | 100 | 50 |
| CH3-C8-BER | >100 | 12.5 | 12.5 | 12.5 | 12.5 |
| CHL | 6 | 2.5 | >100 | 12.5 | >100 |
1 The MIC values were determined using the double-dilution method. The MIC for each compound was determined in triplicate in two independent sets.