. Author manuscript; available in PMC: 2023 Nov 1.

Published in final edited form as: Trop Med Int Health. 2022 Oct 31;27(11):990–998. doi: 10.1111/tmi.13823

Table 2.

Adverse birth outcomes among infants born to women in Botswana, by CP exposure.

Adverse Birth Outcomes	CP (n=5,883)	No CP (n=17,150)	Unadjusted Odds Ratio (95% CI)	Adjusted Odds Ratio (95% CI)
Preterm Delivery	998 (16.96)	3,031 (17.62)	0.96 (0.88 – 1.03)	0.95 (0.87 – 1.03)
Very Preterm Delivery ^*	345 (5.86)	1,167 (6.80)	0.85 (0.75 – 0.97)	0.85 (0.75 – 0.97)
Neonetal Death ^*	59 (1.03)	260 (1.55)	0.65 (0.50 – 0.87)	0.66 (0.49 – 0.88)
Stillbirth	117 (1.99)	346 (2.02)	0.99 (0.79 – 1.21)	1.04 (0.84 – 1.29)
SGA	962 (16.35)	2754 (16.06)	1.02 (0.94 – 1.10)	1.03 (0.95 – 1.12)
Very SGA	410 (6.97)	1,097 (6.40)	1.10 (0.97 – 1.23)	1.08 (0.96 – 1.22)

The data are n (%), unadjusted odds ratio (95% CI) or adjusted odds ratio (95% CI). All models were adjusted for HIV status, maternal age, gravida, occupation, and educational attainment. CP = Chloroquine and Proguanil. Adverse birth outcomes among women from three (Nyangabwe, Ghanzi, Maun, Total, N=23,033) government hospitals in Botswana.

indicates a statistically significant reduction in adjusted odds ratio (p-value < 0.05). CI = Confidence Interval.