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A proposed work model of NOOT protecting against acute liver injury caused by CCl4 exposure. MDA, malondialdehyde; CAT, catalase; SOD, superoxide dismutase; Nrf2, NF-E2-related factor; NF-κB, nuclear factor-kappaB; IL-1β, interleukin-1β; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; HO-1, heme oxygenase-1; ARE, antioxidant response element.
