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. 2023 Jan 15;12(1):202. doi: 10.3390/antiox12010202

Figure 3.

Figure 3

The protective effects of r-Hcy and methionine on erythrocytes osmotic fragility under oxidative stress. (A) The fragility curve shifted to the right after treatment of erythrocytes with Rosup for 6 h, with 50% hemolysis at 0.43 ± 0.01% NaCl solution. The 0.05~0.8 mM r-Hcy treatment resulted in the fragility curves of Rosup-treated erythrocytes shifted back to the left. (B) The fragility curve shifted to the right after treatment of erythrocytes with Rosup for 6 h, with 50% hemolysis at 0.45 ± 0.03% NaCl solution, and 0.1~2 mM methionine treatment inhibited Rosup-induced erythrocytes osmotic fragility elevation in a dose-dependent manner (n = 4).