Table 3.
Minimum inhibitory concentrations (MIC) (μg/mL) and fractional inhibitory concentration indices (FICI) of kuraridin and epicatechin gallate (ECG) with or without gentamicin against gentamicin (Gen) resistant MRSA strains.
| Strains | MIC Alone (μg/mL) | MIC Combine (μg/mL) | FIC | FICI | Outcome | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| ECG | Kur | Gen | ECG | Kur | Gen | ECG | Kur | Gen | |||
| W231 | 512 | 8 | 64 | 0.25 | 2 | 1 | 0.0004 | 0.25 | 0.015 | 0.27 | Synergy |
| 512 | 8 | - | 4 | 2 | - | 0.008 | 0.25 | - | 0.26 | Synergy | |
| W233 | 512 | 8 | 512 | 0.25 | 4 | 16 | 0.0005 | 0.5 | 0.03 | 0.53 | Additive |
| 512 | 8 | - | 16 | 8 | - | 0.03 | 1 | - | 1.03 | Indiffferent | |
| W238 | 512 | 8 | 512 | 0.25 | 2 | 16 | 0.0004 | 0.25 | 0.03 | 0.28 | Synergy |
| 512 | 8 | - | 0.5 | 4 | - | 0.0004 | 0.5 | - | 0.50 | Synergy | |