Table 6.
S. aureus Strains | Resistance | Mechanism |
---|---|---|
1199B | ciprofloxacin | overexpression of the NorA efflux pump |
RN4220-pUL5054 | erythromycin | multicopy plasmid pUL5054 coding for MsrA |
APH2″-AAC6′ | gentamicin | experimentally induced aminoglycosides resistance by methylation of specific nucleotides within the A-site of rRNA (aminoglycoside- 6′-N-acetyltransferase/2″-O- phosphoryl transferase) |
APH3′ | kanamycin | experimentally induced aminoglycosides resistance by methylation of specific nucleotides within the A-site of rRNA (aminoglycoside-3′-O- phosphoryl transferase) |
ANT4′ | fusidic acid | experimentally induced aminoglycosides resistance by methylation of specific nucleotides within the A-site of rRNA (aminoglycoside-4′-O- phosphoryl transferase) is |
MSSA ATCC25923 a | methicillin-sensitive | Control strain |
a Methicillin-sensitive strain (MSSA) used as a control for the current study.