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. 2023 Jan 8;12(1):117. doi: 10.3390/antibiotics12010117

Table 6.

The S. aureus strains with known resistance mechanism used in the study.

S. aureus Strains Resistance Mechanism
1199B ciprofloxacin overexpression of the NorA efflux pump
RN4220-pUL5054 erythromycin multicopy plasmid pUL5054 coding for MsrA
APH2″-AAC6′ gentamicin experimentally induced aminoglycosides resistance by methylation of specific nucleotides within the A-site of rRNA (aminoglycoside- 6′-N-acetyltransferase/2″-O- phosphoryl transferase)
APH3′ kanamycin experimentally induced aminoglycosides resistance by methylation of specific nucleotides within the A-site of rRNA (aminoglycoside-3′-O- phosphoryl transferase)
ANT4′ fusidic acid experimentally induced aminoglycosides resistance by methylation of specific nucleotides within the A-site of rRNA (aminoglycoside-4′-O- phosphoryl transferase) is
MSSA ATCC25923 a methicillin-sensitive Control strain

a Methicillin-sensitive strain (MSSA) used as a control for the current study.