Fig. 1.

Effect of radiation on the activation of NF-κB in mice cochleae. A: Western blot analysis of p65 in the cytoplasm and nucleus of cochlear tissues. β-actin or PCNA were used as internal controls. β-actin was undetectable in the nuclear fraction and PCNA was undetectable in the cytosolic fraction. B: Relative expression levels of p65 in cytoplasm and nucleus at different time points. The relative expression levels of p65 in the nucleus increased while those in the cytoplasm decreased after radiation of the cochleae compared with WT mice. ^* = P < 0.05.