Figure 6.

Pathways and gene ontology (GO) enriched in the immune subtypes of ACC. The KEGG pathways highly enriched in Immunity-H and Immunity-L in TCGA-ACC (A,B). (C) Spearman correlations between the enrichment scores of pathways upregulated in Immunity-H, Immunity-L, and immune scores in ACC. The correlation coefficients (ρ) and p-values are shown. * p < 0.5, ** p < 0.01, *** p < 0.001. (D) Eight gene modules that significantly differentiated ACC by subtype, survival time, or survival status identified by WGCNA. (E) Comparisons of stromal scores evaluated by ESTIMATE [7] between the immune subtypes of ACC (one-tailed Mann–Whitney U test, p < 0.01).