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. 2022 Dec 23;12(1):28. doi: 10.3390/biology12010028

Figure 4.

Figure 4

(A) An enrichment analysis of the 42 metabolites from the combined NMR and LC-MS metabolomics data set with a statistically significant change in hepatocyte cells following ethanol exposure. (B–E) Representative box plots of metabolites from the top enriched pathways in (A) that highlight the top metabolite changes in the metabolomics data sets. All the metabolites demonstrated a fold change >2.0 and an FDR p-value < 0.001 using the Benjamini-Hochberg method. Compound class and names are listed above the box plots. *** p-value < 0.001.