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. 2022 Dec 27;13(1):58. doi: 10.3390/biom13010058

Figure 5.

Figure 5

FGE-based signature for on-treatment samples (FGE-ON) (a–c) Heatmap representing the single sample gene set enrichment analysis value of on-treatment nonresponders (NR) and responders (R) in the Gide et al., MGH, and Abril-Rodriguez et al. cohorts. (d–f) Boxplot of FGE-ON signature scores for on-treatment samples from Gide et al., MGH, and Abril-Rodriguez et al. cohorts. p values were computed via a one-sided Wilcoxon rank-sum test. (g) Receiver operating correlation curve and area under the curve of FGE-ON signatures for on-treatment samples from the Gide et al., MGH, and Abril-Rodriguez et al. cohorts. (h) Receiver operating correlation curve and area under the curve of FGE-ON signatures for on-treatment samples from all test samples, which combined the Gide et al., MGH, and Abril-Rodriguez et al. cohorts. (i–k) Kaplan–Meier curves of PFS for on-treatment samples based on FGE-ON signature scores for all test samples, Gide et al. and MGH cohorts.