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. 2022 Dec 29;13(1):53. doi: 10.3390/bios13010053

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a) Illustration of nucleic acid bioreceptor and bound nucleic acid target. Comparisons of the chemical structures of different nucleic acid subtypes, including (b) DNA, (c) RNA, (d) PNA, (e) LNA, and (f) morpholino, shown as line structures informed by Refs. [73,191].