Table 8.

Demonstrations of SiP biosensors using DNA aptamers as the biorecognition element and their sensing performance. All demonstrations tabulated here used label-free assay formats.

Sensor Type	Target	Detection Performance		Refs.
		Figure of Merit	Value
Si MRR	IgE	LoD	33 pM	[24]
	Thrombin	LoD	1.4 nM
Si MRR	Thrombin	Min. detected concentration	500 pM	[174]
SiOxNy MRR	Aflatoxin M1	LoD	5 nM	[25]
SiOxNy MRR	Aflatoxin M1	Min. detected concentration	1.58 nM	[185]
Si PhC total internal reflection	Cardiac troponin I	LoD	0.1 ng/mL	[164]
Porous Si reflectometric interference spectroscopy	Insulin	LoD	1.9 µg/mL	[176]