Table 26.

Advantages and limitations of lipid nanodiscs as bioreceptors.

Advantages	Limitations
Solubilize and stabilize membrane proteins for studying cell membrane interactions [151] Better consistency, production, monodispersity, production yield, and control over lipid composition than other cell membrane mimics [150,151] Easy immobilization by physisorption [150] Regenerable [148,149]	Poor selectivity, but can be improved by incorporation of membrane proteins [148,149,150] Limited availability; usually custom synthesized in lab [151] Biosensing applications are mainly limited to the study of cell membrane interactions