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. 2022 Dec 29;11(1):91. doi: 10.3390/biomedicines11010091

Figure 7.

Figure 7

ANCOM volcano plot of statistical differences between treatment groups (WT BC & Ztm BC) and control groups (WT Ctr & Ztm Ctr) at genus level. (a): WT f BC harbor a significant increased abundance of Eubacterium (Ruminococcaceae family) and a significantly reduced abundance of Tyzzerella (Lachnospiraceae family) and Dubosiella (Erysipelotrichaceae family) compared with control group. (b): WT m BC harbor a significantly increased abundance of Lactococcus (Streptococcaceae family) and a significantly reduced abundance of Clostridium sensu stricto 1 (Clostridiaceae family) compared with control group. (c): Ztm f BC harbor a significantly reduced abundance of Coriobacteriaceae UCG-002 (Atopobiaceae family) and Peptococcus (Peptococcaceae family) compared with control group. (d): Ztm m BC harbor a significantly reduced abundance of Lachnospiraceae UCG-001 (order Clostridia), Desulfovibrio (Desulfovibrionacea family), and Mucispirillum (Deferribacteraceae family) and a significant increased abundance of UCG-010 (order Oscillospirales) compared with control group. WT = wild-type mice; Ztm = zonulin transgenic mice; Ctr = control mice; BC = bovine colostrum treatment; f = female; m = male.