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. 2023 Jan 7;13(1):127. doi: 10.3390/biom13010127

Figure 5.

Figure 5

PPI network of CRGs in OA. (A) The PPI network of 11 CRGs had 11 nodes and 35 edges. (B) The PPI network of four hub CRGs. CRGs, cuproptosis-related genes; PPI, protein–protein interaction; OA, osteoarthritis. (C) The cohesive regulatory interaction network of four hub gene–TF. Herein, the square nodes were TFs, and gene symbols interacted with TFs as circle nodes. TF, Transcription factors. (D) The interconnected regulatory interaction network of four hub gene–miRNA. Herein, the square node indicated miRNAs and gene symbols interacted with miRNAs as a circle shape. miRNAs, microRNAs.