Table 3.
Comparison of HPV L1 levels between selected groups.
| Variable | L1 Level | MD (95% CI) | p |
|---|---|---|---|
| Histological outcome (with outliers) | |||
| CIN 1 (n = 38) | 1504.62 (154.65; 8683.80) | - | 0.002 |
| CIN 2 (n = 24) | 3684.91 (90.45; 10,905.76) | ||
| CIN 3 (n = 19) | 13,566.25 (2099.17; 25,884.17) | ||
| No pathology (n = 4) | 25,123.51 (20,563.59; 33,437.23) | ||
| Histological outcome (with outliers) | |||
| CIN 1 (n = 38) | 1504.62 (154.65; 8683.80) 3684.91 (90.45; 10,905.76) |
0.022 | |
| CIN 2 (n = 24) CIN 3 (n = 19) |
13,566.25 (2099.17; 25,884.17) | ||
| Histological outcome (with outliers) | |||
| CIN 1 + CIN 2 (n = 62) | 1967.74 (133.21; 8713.67) | 11,598.51 (949.47; 14,437.27) | 0.006 |
| CIN 3 (n = 19) | 13,566.25 (2099.17; 25,884.17) | ||
| 16 | |||
| Yes (n = 40) | 5107.77 (136.04; 17,349.82) | −685.53 (−4112.92; 795.55) | 0.666 |
| No (n = 45) | 4422.24 (229.53; 13,566.25) | ||
| 18 | |||
| Yes (n = 5) | 8713.67 (5009.37; 9210.31) | −4368.77 (−8457.52; 9937.55) | 0.519 |
| No (n = 80) | 4344.90 (145.63; 14,213.32) | −685.53 (−4112.92; 795.55) | 0.666 |
| 31 | |||
| Yes (n = 12) | 1753.24 (351.93; 6430.07) | 3256.13 (−1259.63; 6586.21) | 0.579 |
| No (n = 73) | 5009.37 (154.65; 13,957.17) | −4368.77 (−8457.52; 9937.55) | 0.519 |
| 45 | |||
| Yes (n = 4) | 10,806.31 (4408.50; 17,007.96) | −6384.07 (−12,808.30; 8262.89) | 0.514 |
| No (n = 81) | 4422.24 (154.65; 13,688.40) | 3256.13 (−1259.63; 6586.21) | 0.579 |
| 6 | |||
| Yes (n = 9) | 593.55 (117.89; 13,566.25) | 4514.22 (−2642.35; 6453.08) | 0.424 |
| No (n = 76) | 5107.77 (192.09; 13,822.78) | −6384.07 (−12,808.30; 8262.89) | 0.514 |
| More than one HPV genotype | |||
| Yes (n = 37) | 5008.66 (402.65; 12,928.81) | −55.34 (−2553.91; 2034.14) | 0.601 |
| No (n = 48) | 4953.32 (115.79; 17,093.67) | 4514.22 (−2642.35; 6453.08) | 0.424 |
| Comorbidities | |||
| Yes (n = 26) | 5206.17 (1126.42; 14,469.47) | −3038.83 (−4752.51; 1344.42) | 0.442 |
| No (n = 59) | 2167.34 (192.09; 13,247.53) | −55.34 (−2553.91; 2034.14) | 0.601 |
CIN—cervical intraepithelial neoplasia; HPV—human papillomavirus. MD 95% CI—the median difference with the 95% confidence interval. Comparisons were made with the Mann–Whitney U test when comparing the levels of a variable between two groups or with the Kruskal–Wallis test when there were more than two groups.