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CBD upregulates the expression of osteogenic/odontogenic and angiogenic markers in DPSCs. (A) mRNA level expression pattern of osteogenic/odontogenic and angiogenic markers in DPSCs. (B,C) Western blot analysis and quantification of COL−I and RUNX2 at day 14. Immunohistochemistry analysis of OPN (D,E) and COL−I (F,G) expression in DPSCs at day 3. Scale bar: 50 μm. Significant effect of the treatment compared to the control group, * p < 0.05, ** p < 0.01, and *** p < 0.001.
