| HCC | hepatocellular carcinoma; |
| LASSO | least absolute shrinkage and selection operator; |
| TCGA | cancer Genome Atlas; |
| TMB | tumor mutation burden; |
| OS | overall survival; |
| TME | tumor microenvironment; |
| BM | butyrate matabolism |
| BMGs | butyrate matabolism- related gene signature |
| CR | complete response |
| PR | partial response |
| AUC | area under curve |