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. 2023 Jan 3;11(1):115. doi: 10.3390/biomedicines11010115

Table 3.

Summary of translational studies of natural anti-inflammatory agents targeting inflammatory pathways.

S. No. Patent No. Natural Anti-Inflammatory Agent Target Method of Treatment Reference
1. US8937050B2

  • Glucosinolates

  • Sulforaphane

 Cellular stress response Improvements in behavioral symptoms comprise one or more of the following: a decrease in

  • Irritability,

  • Hyperactivity,

  • Stereotypy, and/or

  • Inappropriate speech

 [101]
2. US20110104100A1

  • Reseveratrol

  • Quercetin

  • Glutathione

 IL-10, IL-4, or TGF family members Method of treating a pervasive developmental disorder comprising:

  • Providing an agent with ability to inhibit host inflammatory reactions,

  • Providing an agent or therapy capable of mobilizing endogenous stem cells, and

  • Administering an effective amount of the agent with ability to inhibit host inflammatory reactions and an effective amount of the agent or therapy capable of mobilizing endogenous stem cells

 [102]