Table 2.

Metabolites identified as significantly different in heart failure.

Metabolite	Tstat	p Value	= –LOG(10p)	FDR
Cis-Aconitic Acid	−5.44	9.09 × 10−7	6.04	9.25 × 10−5
Isocitric acid	−5.35	1.28 × 10−6	5.89	9.25 × 10−5
Glutathione	−4.87	7.56 × 10−6	5.12	2.81 × 10−4
Unknown 115100 5965.5 18950.1	−4.87	7.76 × 10−6	5.11	2.81 × 10−4
Citric acid	−4.43	3.76 × 10−5	4.42	1.09 × 10−3
DL-gamma-methyl-ketoglutaramate	−4.31	5.77 × 10−5	4.24	1.39 × 10−3
4-Hydroxyphenylacetic acid	−4.11	1.16 × 10−4	3.93	2.11 × 10−3
Linoleic acid C18_2n-6,9c	4.12	1.57 × 10−4	3.80	1.62 × 10−2
Beta-Alanine	−3.96	1.89 × 10−4	3.72	6.84 × 10−3
Fumaric acid	−3.96	1.90 × 10−4	3.72	3.06 × 10−3
Cis-Vaccenic acid C18_1n-7c	4.01	2.23 × 10−4	3.65	1.62 × 10−2
Unknown 113100 8548.1 5921.2	−3.84	2.80 × 10−4	3.55	3.51 × 10−3
Malic acid	−3.84	2.89 × 10−4	3.54	3.51 × 10−3
Unknown 127100 15949.8 5948.8	−3.56	7.02 × 10−4	3.15	6.37 × 10−3
Itaconic acid	−3.76	3.72 × 10−4	3.43	4.15 × 10−3
Unknown 114100 14731.9 11527.2	−3.61	6.07 × 10−4	3.22	5.87 × 10−3
Pentadecanoic acid C15_0	3.67	6.35 × 10−4	3.20	2.65 × 10−2
Unknown 125100 18490.5 9654.3	−3.56	7.02 × 10−4	3.15	6.37 × 10−3
Ornithine	−3.36	1.32 × 10−3	2.88	1.12 × 10−2
Cysteine	−3.41	1.35 × 10−3	2.87	3.23 × 10−2
11,14-Eicosadienoic C20_2n-6,9c	3.34	1.67 × 10−3	2.78	3.46 × 10−2
Malonic acid	−3.28	1.71 × 10−3	2.77	1.37 × 10−2
Glutamic acid	−3.19	2.22 × 10−3	2.65	4.03 × 10−2
Succinic acid	−3.14	2.55 × 10−3	2.59	1.95 × 10−2
Arachidic acid C20_0	3.17	2.68 × 10−3	2.65	4.03 × 10−2
2-Hydroxyisobutyric acid	−3.04	3.41 × 10−3	2.47	2.47 × 10−2
Unknown 128100 13921.1 4219.1	−2.85	5.87 × 10−3	2.23	3.87 × 10−2
Adipic acid	−2.78	7.07 × 10−3	2.15	4.46 × 10−2

T stat = T statistic, FDR = False discovery rate.