Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Consurf analysis of Mpro structure: ConSurf analysis showing conserved regions in the three-dimensional structure of Mpro. (A) Surface view showing the highly conserved substrate-binding site (red broken circle) and region involved in homodimerization (broken blue circle). Drugs were docked in the substrate-binding region of Mpro. (B) Cartoon representation showing the conserved regions in Mpro. The residues forming the substrate-binding pocket are shown in stick representation.
