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. 2022 Dec 8;5(12):e2245826. doi: 10.1001/jamanetworkopen.2022.45826

Table 1. Maternal and Neonatal Characteristics.

Characteristics Infants with LOM, No./total No. (%) (n = 167) Infants with LOS and no LOM, No./total No. (%) (n = 4564) Infants with no LOS or LOM, No./total No. (%) (n = 8641) P valuea
Maternal
Maternal age, median (IQR), yb 26.0 (22.0-31.0) 27.0 (22.0-32.0) 27.0 (23.0-32.0) .002
Maternal education
<High school 34/124 (27) 851/3437 (25) 1468/6483 (23) .002
High school degree 37/124 (30) 1087/3437 (32) 1914/6483 (30)
Partial college, trade, technical 34/124 (27) 790/3437 (23) 1608/6483 (25)
≥College degree 19/124 (15) 709/3437 (21) 1493/6483 (23)
Private medical insurance 51/154 (33) 1646/4214 (39) 3384/7812 (43) <.001
Race
Black 63/166 (38) 1908/4485 (43) 3524/8465 (42) .17
White 95/166 (57) 2352/4485 (52) 4439/8465 (52)
Otherc 8/166 (5) 225/4485 (5) 502/8465 (6)
Hispanic 28/161 (17) 816/4441 (18) 1325/8397 (16) <.001
Maternal diabetes 8/166 (5) 211/4549 (5) 395/8613 (5) .98
Maternal hypertension 22/166 (13) 950/4553 (21) 1891/8609 (22) .01
Histological chorioamnionitisd 61/115 (53) 1511/3112 (49) 3322/6788 (49) .63
Antenatal steroids 145/165 (88) 3856/4545 (85) 7461/8608 (87) .01
Antibiotics within 72 h of deliveryd 89/94 (95) 2215/2416 (92) 4980/5440 (92) .55
Multiple gestation 40/167 (24) 1106/4564 (24) 2055/8641 (24) .85
Cesarean section 90/167 (54) 2723/4561 (60) 5482/8629 (64) <.001
Neonatal
Outborn 12/167 (7) 399/4564 (9) 588/8641 (7) <.001
Sex
Female 86/167 (51) 2063/4561 (45) 4365/8640 (50) <.001
Male 81/167 (49) 2498/4561 (55) 4285/8640 (50)
Gestational age, median (IQR), wke 25.0 (24.1-25.9) 25.0 (24.1-25.9) 25.6 (24.6-26.3) <.001
Birth weight, median (IQR), ge 699 (605-838) 700 (600-810) 750 (636-870) <.001
Small for gestational age 9/167 (5) 330/4561 (7) 566/8640 (7) .26

Abbreviations: LOM, late-onset meningitis; LOS, late-onset sepsis.

a

P values were calculated from χ2 tests for categorical variables and Kruskal-Wallis tests for continuous variables.

b

Data on maternal age were available for 167 participants in the LOM cohort, 4562 in the LOS without LOM cohort, and 8636 in the no LOS or LOM cohort.

c

Races included in other were American Indian or Alaskan Native (82 participants); Asian, Native Hawaiian, or other Pacific Islander (483 participants); more than 1 race (107 participants); and unknown race (63 participants).

d

Available after 2006.

e

Data on gestational age and birth weight were available for 167 participants in the LOM cohort, 4564 participants in the LOS without LOM cohort, and 8641 participants in the no LOS or LOM cohort.