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. 2022 Dec 9;5(12):e2245861. doi: 10.1001/jamanetworkopen.2022.45861

Table 2. Odds Ratios Associated With a Positive SARS-CoV-2 Test for Participants Reporting Contact With an Individual With SARS-CoV-2 in the Past 2 Weeks Based on Vaccination Status and Reported Symptoms of the Contact.

Date Participants, No. OR (95% CI) P valueb OR (95% CI) P valuec
Contact with vaccinated casea Contact with unvaccinated casea Contact with asymptomatic casea Contact with symptomatic casea
October 2021 –July 2022d,e 2355 2.03 (1.56-2.76) 4.04 (2.39-7.23) .04 1.80 (1.23-2.67) 2.78 (2.07-3.91) .15
December 2021– July 2022f,g 1589 1.68 (1.26-2.31) 2.77 (1.54-5.31) .33 1.44 (0.95-2.23) 2.16 (1.55-3.04) .27
a

Reference group is participants not reporting contact with a case.

b

P value for comparison between unvaccinated contact and vaccinated contact using Tukey honest significant difference test.

c

P value for comparison between symptomatic contact and asymptomatic contact using Tukey honest significant difference test.

d

Adjusted for age, sex, race and ethnicity, region, social and economic risk index, cough, sore throat, fever, loss of smell or taste, attending or working at school, prior positive test, vaccination status of participant, log of cases reported in community, and dominant variant.

e

Includes all cases within date range (Delta, Omicron, and undetermined).

f

Adjusted for age, sex, race and ethnicity, region, social and economic risk index, cough, sore throat, fever, loss of smell or taste, attending or working at school, prior positive test, vaccination status of participant, and log of cases reported in community.

g

Includes presumed Omicron cases only.