Table 2.
Median overall survival and 95% CI for molecular AML classes.
| Molecular Classes | OS | (95% CI) | p | |
|---|---|---|---|---|
| Lower IC | Upper IC | |||
| inv(16) | NR | <0.001 | ||
| CEBPA bZIP | NR | |||
| No events | NR | |||
| NPM1 | 29.0 | 19.9 | 38.0 | |
| Not class defining mutations | 23.3 | 11.0 | 35.6 | |
| DNMT3A/IDH1–2 | 18.5 | 1.7 | 35.3 | |
| sAML1 | 18.1 | 12.5 | 23.7 | |
| t(8;21) | 17.5 | 3.7 | 31.3 | |
| Trisomies | 14.4 | |||
| t(X;11) | 13.2 | 0.0 | 31.3 | |
| sAML2 | 12.1 | 9.9 | 14.2 | |
| TP53–CK | 5.3 | 2.9 | 7.6 | |
| inv(3) | 4.9 | 0.8 | 9.1 | |
| WT1 | 4.0 | 0.0 | 18.4 | |
NR: Mean overall survival not reached at: “inv(16)”: 42 months; “No events”: 33 months and “CEBPA bZIP”: 31 months.